Giacomo Cappon

Giacomo Cappon

Assistant Professor (RTD-A)

Department of Information Engineering · University of Padova

42
Journal Papers
2352
Citations (Scholar)
h=20
H-index (Scholar)
39
Papers in Q1
2
Int'l Patents

About

I am a Tenure-Track Assistant Professor (RTT, SSD IBIO-01/A) at the Department of Information Engineering (DEI) of the University of Padova, Italy, where I have been working since my Bachelor's degree in 2011.

My primary field of research is the development of artificial intelligence (AI)-driven decision support systems (DSS) and digital twin frameworks for optimizing diabetes therapy, with a particular focus on type 1 diabetes and glucose–insulin dynamics. My work spans the conception, implementation, and clinical assessment of algorithmic solutions that merge physiological modeling, wearable sensor data, and personalized therapy optimization.

I am the Principal Investigator of the DIANA project (Fondo Italiano per la Scienza 2024–2025, €1M+), and I collaborate with major international partners including Roche Diagnostics, Dexcom Inc., Imperial College London, University of Oxford, University of Bern, and Woman's Hospital (Baton Rouge, LA). I hold 2 international patent applications, both with IP transferred to international companies.

🧬AI Decision Support Systems
🔄Digital Twin Frameworks
📡Continuous Glucose Monitoring
🩺Type 1 Diabetes Management
📱Wearable Sensor Data
📊Bayesian & Probabilistic Modeling

Academic Positions

May 2026 – Today
Tenure-Track Assistant Professor (RTT)
Department of Information Engineering, University of Padova, Italy
Sep 2023 – May 2026
Assistant Professor (RTD-A)
Department of Information Engineering, University of Padova, Italy
Dec 2021 – Aug 2023
Postdoctoral Research Fellow (Senior)
Department of Information Engineering, University of Padova, Italy
Dec 2019 – Nov 2021
Postdoctoral Research Fellow (Junior)
Department of Information Engineering, University of Padova, Italy
Oct 2016 – Sep 2019
PhD Student
Department of Information Engineering, University of Padova, Italy

Education

Mar 2020
PhD in Information Engineering
University of Padova – Thesis: "Open-loop insulin dosing personalization in type 1 diabetes using CGM data and patient characteristics" (Winner of the GNB PhD Thesis Award)
Sep 2016
M.Sc. in Bioengineering
University of Padova
Sep 2014
B.Sc. in Information Engineering
University of Padova

Publications

42 journal papers · 19 Scopus-indexed conference papers · 2 international patents · 2352 citations (Scholar) · H-index 20

J42
Relationship between continuous maternal intrapartum and postpartum glucose monitoring metrics and neonatal outcomes and postpartum glucose metabolism in individuals with gestational diabetes
K. E. Elkind-Hirsch, M. Armatta, E. Veillon, S. Schiavon, and G. Cappon
BMC Pregnancy and Childbirth, accepted Mar 2026, in press
Q1
J41
Feasibility and Benefits of Continuous Glucose Monitoring for Type 1 Diabetes in Rwanda: A Real-World 12-month Continuation Phase
S. Narayanan, J. Baker, J. Welsh, G. Cappon, J. C. Habineza, and S. P. Niyonsenga
Diabetes Medicine, accepted Feb 2026, in press
Q1
J40
Clinical efficacy evaluation of a CGM-guided forecasting algorithm to mitigate postprandial hypoglycaemia
A. Journeaux et al. (incl. G. Cappon)
Diabetes Technology & Therapeutics, accepted Feb 2026, in press
Q1
J39
Developing effective machine learning models for insulin bolus calculation in type 1 diabetes exploiting real-world data and digital twins
E. Pellizzari, G. Cappon, G. Nicolis, G. Sparacino, and A. Facchinetti
IEEE Transactions on Biomedical Engineering, online ahead of print, Nov 2025. DOI: 10.1109/TBME.2025.3648515
Q1DOI
J38
Data Augmentation via Digital Twins Enables the Development of Personalized Deep Learning Glucose Prediction Algorithms for Type 1 Diabetes in Poor Data Context
F. Prendin, A. Facchinetti, and G. Cappon (corresponding author)
IEEE Transactions on Biomedical Engineering, online ahead of print, Nov 2025. DOI: 10.1109/TBME.2025.3635264
Q1DOI
J37
Systematic Review on Deep Learning Algorithms for Blood Glucose Forecasting in Type 1 Diabetes
A. Calzavara, F. Prendin, G. Cappon, S. Del Favero, and A. Facchinetti
IEEE Journal of Biomedical and Health Informatics, online ahead of print, Nov 2025. DOI: 10.1109/JBHI.2025.3630214
Q1DOI
J36
Continuous glucose monitoring (CGM) in early gestational diabetes (GDM) improves maternal and neonatal outcomes – The Steady Sugar trial
K. Elkind-Hirsch et al. (incl. G. Cappon)
Diabetes, Obesity and Metabolism, online ahead of print, Oct 2025. DOI: 10.1111/dom.70254
Q1DOI
J35
Exploring Relationships Between Maternal Characteristics, Continuous Glucose Monitoring Data, and Neonatal Hypoglycemia in Gestational Diabetes Pregnancies Using Probabilistic Modeling
G. Cappon, M. Catanuso, E. Tavazzi, K. Elkind-Hirsch, and A. Facchinetti
Journal of Diabetes Science and Technology, in press, Sep 2025. DOI: 10.1177/19322968251388107
Q1DOI
J34
AirPredict: An eHealth Platform for Asthma Management Leveraging Wearable Sensors, Digital Diaries, and Air Quality Monitoring
M. Atzeni, S. Gaiotti, L. Cossu, G. Cappon, M. Tinè, et al.
Frontiers in Digital Health, vol. 6, Jun 2025. DOI: 10.3389/fdgth.2025.1573342
Q1DOI
J33
Automatic identification of unreported meals from continuous glucose monitoring data in individuals after bariatric surgery using a template match-based algorithm
E. Pellizzari, F. Prendin, G. Cappon, E. Idi, S. Del Favero, D. Herzig, L. Bally, and A. Facchinetti
Scientific Reports, vol. 15, no. 1, Mar 2025. DOI: 10.1038/s41598-025-92275-3
Q1DOI
J32
Towards a decision support system for post bariatric hypoglycaemia: development of forecasting algorithms in unrestricted daily-life conditions
F. Prendin, O. Stricher, G. Cappon, E. Rolfes, D. Herzig, L. Bally, and A. Facchinetti
BMC Medical Informatics and Decision Making, vol. 25, no. 1, Jan 2025. DOI: 10.1186/s12911-025-02856-5
Q1DOI
J31
A Machine Learning Framework for Short-Term Prediction of Chronic Obstructive Pulmonary Disease Exacerbations Using Personal Air Quality Monitors and Lifestyle Data
M. Atzeni, G. Cappon, J. K. Quint, F. Kelly, B. Barratt, and M. Vettoretti
Scientific Reports, vol. 15, no. 1, Jan 2025. DOI: 10.1038/s41598-024-85089-2
Q1DOI
J30
Continuous Glucose Monitoring Among Patients with Type 1 Diabetes in Rwanda (CAPT1D) Phase I: Feasibility Study
J. Baker, G. Cappon, J. C. Habineza, C. Basch, S. Mey, et al.
JMIR Formative Research, vol. 9, Nov 2024. DOI: 10.2196/64585
Q2DOI
J29
Automated Pipeline for Denoising, Missing Data Processing, and Feature Extraction for Signals acquired via Wearable Devices in MS and ALS Applications
L. Cossu, G. Cappon, and A. Facchinetti
Frontiers in Digital Health, vol. 6, Sep 2024. DOI: 10.3389/fdgth.2024.1402943
Q1DOI
J28
Adaptive and self-learning Bayesian filtering algorithm to statistically characterize and improve signal-to-noise ratio of heart-rate data in wearable devices
L. Cossu, G. Cappon, and A. Facchinetti
Journal of the Royal Society Interface, vol. 21, no. 218, Sep 2024. DOI: 10.1098/rsif.2024.0222
Q1DOI
J27
HIT4HYPOS CGM analysis: The effects of High Intensity Interval Training on glycaemia in people with type 1 diabetes and impaired awareness of hypoglycaemia
C. Farrell and G. Cappon (co-first author), D. West, A. Facchinetti, and R. J. McCrimmon
Journal of Diabetes Science and Technology, online ahead of print, Sep 2024. DOI: 10.1177/19322968241273845
Q1DOI
J26
Digital twins in type 1 diabetes: A systematic review
G. Cappon and A. Facchinetti
Journal of Diabetes Science and Technology, Jun 2024. DOI: 10.1177/19322968241262112
Q1DOI
J25
drCORRECT: An algorithm for the preventive administration of postprandial corrective insulin boluses in type 1 diabetes management
E. Pellizzari, F. Prendin, G. Cappon, G. Sparacino, and A. Facchinetti
Journal of Diabetes Science and Technology, Dec 2023. DOI: 10.1177/19322968231221768
Q1DOI
J24
High intensity interval training as a novel treatment for impaired awareness of hypoglycaemia in people with type 1 diabetes (HIT4HYPOS): A randomised group parallel study
C. Farrell, A. D. McNeilly, S. Hapca, P. Fournier, T. Jones, A. Facchinetti, G. Cappon, D. West, and R. J. McCrimmon
Diabetologia, vol. 67, no. 2, Feb 2024. DOI: 10.1007/s00125-023-06051-x
Q1DOI
J23
Design and usability assessment of a user-centered, modular platform for real-world data acquisition in clinical trials involving post-bariatric surgery patients
L. Cossu, G. Cappon, O. Streicher, D. Herzig, L. Bally, and A. Facchinetti
Journal of Diabetes Science and Technology, Dec 2023. DOI: 10.1177/19322968231220061
Q1DOI
J22
The importance of interpreting machine learning models for blood glucose prediction in diabetes: an analysis using SHAP
F. Prendin, J. Pavan, G. Cappon, S. Del Favero, G. Sparacino, and A. Facchinetti
Scientific Reports, vol. 13, Oct 2023. DOI: 10.1038/s41598-023-44155-x
Q1DOI
J21
Relationship between symptom perception and postprandial glycaemic profiles in patients with post-bariatric hypoglycaemia after Roux-en-Y gastric bypass surgery
A. Tripyla, A. Ferreira, K. A. Schönenberger, N. H. Naef, L. E. Inderbitzin, F. Prendin, L. Cossu, G. Cappon, A. Facchinetti, D. Herzig, and L. Bally
Diabetes Care, vol. 46, no. 10, Oct 2023. DOI: 10.2337/dc23-0454
Q1DOI
J20
ReplayBG: a digital twin-based methodology to identify a personalized model from type 1 diabetes data and simulate glucose concentrations to assess alternative therapies
G. Cappon, M. Vettoretti, G. Sparacino, S. Del Favero, and A. Facchinetti
IEEE Transactions on Biomedical Engineering, vol. 70, no. 11, Nov 2023. DOI: 10.1109/TBME.2023.3286856
Q1DOI
J19
Individualized Models for Glucose Prediction in Type 1 Diabetes: comparing black-box approaches to a physiological white-box one
G. Cappon, F. Prendin, A. Facchinetti, G. Sparacino, and S. Del Favero
IEEE Transactions on Biomedical Engineering, vol. 70, no. 11, Nov 2023. DOI: 10.1109/TBME.2023.3276193
Q1DOI
J17
AGATA: A toolbox for automated glucose data analysis
G. Cappon, M. Vettoretti, G. Sparacino, S. Del Favero, and A. Facchinetti
Journal of Diabetes Science and Technology, Jan 2023. DOI: 10.1177/19322968221147570
Q1DOI
J13
An integrated mobile platform for automated data collection and real-time patient monitoring in diabetes clinical trials
G. Cappon, L. Cossu, F. Boscari, D. Bruttomesso, G. Sparacino, and A. Facchinetti
Journal of Diabetes Science and Technology, vol. 16, no. 6, Nov 2022. DOI: 10.1177/19322968211024620
Q1DOI
J8
Continuous glucose monitoring sensors for diabetes management: A review of technologies and applications
G. Cappon, M. Vettoretti, G. Sparacino, and A. Facchinetti
Diabetes & Metabolism Journal, vol. 43, no. 4, Aug 2019. DOI: 10.4093/dmj.2019.0121
Q1DOI
J6
Classification of postprandial glycemic status with application to insulin dosing in type 1 diabetes: An in silico proof-of-concept
G. Cappon, A. Facchinetti, G. Sparacino, P. Georgiou, and P. Herrero
Sensors, vol. 19, no. 14, Jul 2019. DOI: 10.3390/s19143168
Q1DOI
J3
A neural-network-based approach to personalize insulin bolus calculation using continuous glucose monitoring
G. Cappon, M. Vettoretti, F. Marturano, A. Facchinetti, and G. Sparacino
Journal of Diabetes Science and Technology, vol. 12, no. 2, Mar 2018. DOI: 10.1177/1932296818759558
Q1DOI
J1
Heterogeneity and nearest-neighbour coupling can explain small-worldness and wave properties in pancreatic islets
G. Cappon and M. G. Pedersen
Chaos, vol. 26, no. 5, May 2016. DOI: 10.1063/1.4949020
Q1DOI

Open-Source Software

Software tools developed and maintained as part of my research on AI for diabetes management.

🔄
ReplayBG

A digital twin-based methodology to identify a personalized model from type 1 diabetes data and simulate glucose concentrations to assess alternative therapies. Central technological asset of the research group. Licensed to Roche Diagnostics International Ltd.

📊
AGATA

A toolbox for Automated Glucose dATA Analysis. Provides a comprehensive set of tools for statistical analysis of continuous glucose monitoring (CGM) data. Used in collaborations with University of Oxford, University of Dundee, and more.

📱
IMPACT

An integrated mobile platform for automated data collection and real-time patient monitoring in diabetes clinical trials. Enables in-house clinical trials and multi-sensor data collection. Now a core component of the DARE initiative's DSS.

Teaching

Biomedical Wearable Technologies for Healthcare and Wellbeing
Master's Degree in Bioengineering · Department of Information Engineering, University of Padova
AY 2021/22 – Present Professor Responsible Co-designer 48 hours · 6 CFU · ~40–90 students
🏅 Awarded "Progetto per la Premialità della didattica" for AY 2023/24.
Medical Informatics
Master's Degree in Bioengineering · Department of Information Engineering, University of Padova
AY 2019/20 Contract Professor 24 hours · 3 CFU · ~120 students

Selected Research Projects

🏛️
DIANA

Digital Twin and Artificial Intelligence for Adaptive Management of Pediatrics with Type 1 Diabetes under Multiple Daily Injection. Funded by MUR (Fondo Italiano per la Scienza 2024–2025). Budget: €1,036,113. Principal Investigator.

🤝
Roche Agreements

Agreement between DEI-UNIPD and Roche Diagnostics International Ltd. (Rotkreuz, Switzerland). Principal Investigator.

🇪🇺
DARE

Digital Medicine & Health Technologies national initiative (PNC-I.1). Spoke 3 – Wearable technologies and AI for health. Member and work-package contributor.

🌍
BRAINTEASER

EU Horizon 2020 project (Grant #101017598). AI for disease monitoring in ALS and MS using wearable sensors. Budget: €5.9M. Task leader for wearable data preprocessing and feature extraction.

🌬️
BREATHE

Big data, IoT and AI to study the impact of personal exposure to air pollution on asthma exacerbations. National PNRR project. Scientific leader for the DEI-UNIPD unit.

🤝
Dexcom Agreements

Long-term research collaboration with Dexcom Inc. (San Diego, CA). Multiple agreements from 2015–2026. PI of current 2022–2026 and 2025–2026 agreements. Resulted in 2 international patents (IP transferred to Dexcom).

Contact

🏢
Phone
+39 0498277595
📍
Address
DEI – Via Gradenigo 6/B, 35131 Padova, Italy